Neil deGrasse Tyson
Neil is more famous than his meme’s are and that’s quite a feat to accomplish. Most of the subjects in them come from unknown people so it’s very rare that someone famous becomes famous twice over in funny photos.
Roxanne was more than a member of the band. She was actually a huge fan of the Villanova basketball team. When they were eliminated from the NCAA tourney she cried as the band played their final tune of the season. Someone caught a picture of her and “Crying Piccolo Girl” was born.